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Table 1 Utilized scales to evaluate gender-affirming medical treatment outcomes for adolescents

From: Gender-affirming medical treatment for adolescents: a critical reflection on “effective” treatment outcomes

Scale

Object of measure

Source

Body Image Scale (BIS)

Body image satisfaction or dissatisfaction

Carmichael et al. (2021) [20]

 

Satisfaction With Primary, Secondary, and Other Physical Characteristics

Cohen-Kettenis & van Goozen (1997) [64]

 

Body satisfaction

De Vries et al. (2011) [65]

 

Body image

De Vries et al. (2014) [6]

 

Body image dissatisfaction

Grannis et al. (2021) [66]

 

Body dissatisfaction

Kuper et al. (2020); [67]

Smith et al. (2001; 2005) [29, 68]

Utrecht Gender Dysphoria Scale (UGDS)

Intensity of gender dysphoria

Carmichael et al. (2021) [20]

 

Gender dysphoria

Cohen-Kettenis & van Goozen (1997) [64]; Smith et al. (2001; 2005) [29, 68]; De Vries et al. (2011; 2014) [6, 65]

 

GD-related discomfort

Costa et al. (2015) [69]

Youth Self Report (YSR)

Emotional and behavioral problems (psychological functioning)

Becker-Hebly et al. (2021) [19]

 

General psychological functioning, self-harm

Carmichael et al. (2021) [20]

 

Behavioral and emotional problems

De Vries et al. (2011; 2014) [6, 65]

 

Internalizing and externalizing problem behavior, self-harm/suicidality, and poor peer relations

Van der Miesen et al. (2020) [70]

Children’s Global Assessment Scale (CGAS)

Global functioning

Becker-Hebly et al. (2021) [19]; De Vries et al. (2014) [6]

 

Psychological and social functioning

Carmichael et al. (2021) [20]

 

Global Psychosocial Functioning

Costa et al. (2015) [69]

 

Overall severity of disturbance in children

De Vries et al. (2011) [65]

Minnesota Multiphasic Personality Inventory (MMPI) or Dutch version (NVM)

Personality inventory: negativism, somatization, shyness, psychopathology, and extroversion

Cohen-Kettenis & van Goozen (1997) [64]

 

Psychological functioning

Smith et al. (2001; 2005) [29, 68]

Child Behaviour Checklist (CBCL)

General psychological functioning, self-harm

Carmichael et al. (2021) [20]

 

Behavioral and emotional problems

De Vries et al. (2011; 2014) [6, 65]

Adult Self Report (ASR)

Emotional and behavioral problems (psychological functioning)

De Vries et al. (2014) [6]

Becker-Hebly et al. (2021) [19]

Treatment evaluation questionnaire (self-constructed) - satisfaction with surgery

Functionality of the vagina or penis

Cohen-Kettenis & van Goozen (1997) [64]

 

Functionality of the vagina or penis and satisfaction with surgical results

Smith et al. (2001) [29]

 

Functioning of vagina/penis and breasts

Smith et al. (2005) [68]

Trait Anxiety Scale (STAI) of State-Trait Personality Inventory

Tendency to respond with anxiety to a threatening or annoying situation

De Vries et al. (2011; 2014) [6, 65]

Trait Anger Scale (TPI) of State-Trait Personality Inventory

Tendency to respond with anger to a threatening or annoying situation

De Vries et al. (2011; 2014) [6, 65]

Beck Depression Inventory (BDI)

Presence and degree of depression

De Vries et al. (2011) [65]

 

Presence and severity of depressive symptoms

De Vries et al. (2014) [6]

Screen for Child Anxiety Related Emotional Disorders (SCARED)

Symptoms of generalized anxiety

Grannis et al. (2021) [66]

 

Panic-related, social, separation-related, generalized, and school avoidance–related anxiety symptoms

Kuper et al. (2020) [67]

Appraisal of Appearance Inventory (AAI)

(In)compatibility of the appearance with the new gender

Smith et al. (2001) [29]

 

Gender compatibility

Smith et al. (2005) [68]

Dutch version of Symptom Checklist 90 (SCL-90)

Psychological functioning/stability

Smith et al. (2001; 2005) [29, 68]

Patient Health Questionnaire (PHQ-9)

Symptoms of depression

Achille et al. (2020) [71]

 

Depression

Tordoff et al. (2022) [72]

The Social Support Scale

Enquiry about the patient’s eight closest acquaintances

Smith et al. (2005) [68]

The Center for Epidemiological Studies Depression Scale (CESD-R)

Psychological measure - depression

Achille et al. (2020) [71]

Quality of Life Enjoyment and Satisfaction (QLES-Q-SF)

Psychological measure - quality of life

Achille et al. (2020) [71]

Ask Suicide-Screening (ASQ)

Suicidality

Allen et al. (2019) [73]

General Well-Being Scale (GWBS) of the Pediatric Quality of Life Inventory

Well-being

Allen et al. (2019) [73]

Kidscreen-27

Health related quality of life - psychological and physical dimensions

Becker-Hebly et al. (2021) [19]

Short Form-8

Mental and physical quality of life

Becker-Hebly et al. (2021) [19]

Dutch Personality Questionnaire (NPV)

Feelings of inadequacy, social inadequacy, rigidity, hostility, complacency, dominance, and self-esteem

Cohen-Kettenis & van Goozen (1997) [64]

Social Reactions Questionnaire

Reactions of the social environment to the transsexual

Cohen-Kettenis & van Goozen (1997) [64]

Adult Behavioral Checklist (ABCL)

Behavioral and emotional problems

De Vries et al. (2014) [6]

WHOQOL-BREF

Quality of life, subjective well-being

De Vries et al. (2014) [6]

The Satisfaction With Life Scale (SWLS)

Life satisfaction

De Vries et al. (2014) [6]

Subjective Happiness Scale (SHS)

Happiness

De Vries et al. (2014) [6]

Quick Inventory of Depressive Symptoms (QIDS)

Symptoms of depression

Kuper et al. (2020) [67]

Public Confrontation Questionnaire

Evaluate the subject’s experiences of being able to “pass” in the new social role

Smith et al. (2001) [29]

The Affect Balance Scale

Overall psychological well-being

Smith et al. (2001) [29]

GID in Childhood Scale

Presence of GID symptoms in childhood

Smith et al. (2005) [68]

Generalized Anxiety Disorder (GAD-7)

Anxiety, self-harm and suicidal thoughts

Tordoff et al. (2022) [72]

Connor-Davidson Resilience Scale (CD-RISC)

Resilience

Tordoff et al. (2022) [72]

LSAS

Social anxiety

Grannis et al. (2021) [66]

CDI

Depression

Grannis et al. (2021) [66]

SBQ-R

Suicidality/non-suicidal self-injury

Grannis et al. (2021) [66]

Client Satisfaction Questionnaire (ZUF-8)

Youth’s satisfaction with Transition related care (TRC)

Nieder et al. (2021) [74]

Individual Treatment Progress Score (ITPS)

Individual progress with regard to completion of a medical transition

Nieder et al. (2021) [74]

F-SozU

Adolescents’ perceived social support

Nieder et al. (2021) [74]

Kessler-6 Psychological Distress Scale

Severe psychological distress

Turban et al. (2022) [75]

Kidscreen-52

Health related quality of life

Carmichael et al. (2021) [20]

Treatment evaluation and post-treatment functioning

Post-operative functioning and (dis)satisfaction

Smith et al. (2005) [68]

Post-operative Functioning Scale

Postoperative functioning and satisfaction with SR

Smith et al. (2005) [68]

Life circumstances (self-constructed)

Objective and Subjective Well-Being

De Vries et al. (2014) [6]